Lipid phosphatase SHIP‐1 regulates chondrocyte hypertrophy and skeletal development

SH2‐containing inositol‐5′‐phosphatase‐1 (SHIP‐1) controls the phosphatidylinositol‐3′‐kinase (PI3K) initiated signaling pathway by limiting cell membrane recruitment and activation of Akt. Despite the fact that many of the growth factors important to cartilage development and functions are able to...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: So, Eui‐Young, Sun, Changqi, Wu, Keith Q., Driesman, Adam, Leggett, Susan, Isaac, Mauricio, Spangler, Travis, Dubielecka‐Szczerba, Patrycja M., Reginato, Anthony M., Liang, Olin D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879780/
https://ncbi.nlm.nih.gov/pubmed/31287165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29063
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