Loss of lipid phosphatase SHIP1 promotes macrophage differentiation through suppression of dendritic cell differentiation

SH2-containing inositol 5ʹ-phosphatase-1 (SHIP1) deficiency in mice results in abnormal myeloid expansion, and proinflammatory conditions in the lung. However, the mechanisms involved in SHIP1-mediated regulation of myeloid differentiation remain unclear. Here we show that SHIP1 is a key regulator o...

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Publicat a:Cancer Biol Ther
Autors principals: So, Eui Young, Sun, Changqi, Reginato, Anthony M., Dubielecka, Patrycia M., Ouchi, Toru, Liang, Olin D.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343724/
https://ncbi.nlm.nih.gov/pubmed/30277839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1523846
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