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Roles of DNA Damage Response Proteins in Mitogen-Induced Thp-1 Differentiation into Macrophage

ATM, ATR and DNA-PK are critical for DNA damage response (DDR) and sequential repair, leading to genomic stability. In this study, we found the expression of these proteins is markedly induced by PMA during THP1 differentiation without the change in the level of transcripts. Also, inhibitors of thes...

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Detalles Bibliográficos
Publicado en:J Cancer Biol Res
Main Authors: So, Eui Young, Kozicki, Martin, Ouchi, Toru
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313864/
https://ncbi.nlm.nih.gov/pubmed/25654138
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