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Roles of DNA Damage Response Proteins in Mitogen-Induced Thp-1 Differentiation into Macrophage

ATM, ATR and DNA-PK are critical for DNA damage response (DDR) and sequential repair, leading to genomic stability. In this study, we found the expression of these proteins is markedly induced by PMA during THP1 differentiation without the change in the level of transcripts. Also, inhibitors of thes...

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Detalhes bibliográficos
Publicado no:J Cancer Biol Res
Main Authors: So, Eui Young, Kozicki, Martin, Ouchi, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313864/
https://ncbi.nlm.nih.gov/pubmed/25654138
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