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Endothelial to haematopoietic transition contributes to pulmonary arterial hypertension

AIMS: The pathogenic mechanisms of pulmonary arterial hypertension (PAH) remain unclear, but involve dysfunctional endothelial cells (ECs), dysregulated immunity and inflammation in the lung. We hypothesize that a developmental process called endothelial to haematopoietic transition (EHT) contribute...

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Dades bibliogràfiques
Publicat a:Cardiovasc Res
Autors principals: Liang, Olin D., So, Eui-Young, Egan, Pamela C., Goldberg, Laura R., Aliotta, Jason M., Wu, Keith Q., Dubielecka, Patrycja M., Ventetuolo, Corey E., Reginato, Anthony M., Quesenberry, Peter J., Klinger, James R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852529/
https://ncbi.nlm.nih.gov/pubmed/29016733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx161
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