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The SUMO-specific Protease SENP1 deSUMOylates p53 and regulates its activity
The stability and activity of the p53 tumor suppressor protein is tightly regulated by various posttranslational modifications, including SUMOylation. p53 can be modified by both SUMO1 and SUMO2, although how SUMOylation regulates p53 activity is still obscure. Whether p53 activity is directly regul...
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| Izdano u: | J Cell Biochem |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7802976/ https://ncbi.nlm.nih.gov/pubmed/32786121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.29838 |
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