LEDGF DeSumoylation by Sumo-Specific Protease, Senp-1 Regulates Its Transcriptional Activation of Small Heat Shock Protein and Cellular Response

Lens epithelium-derived growth factor (LEDGF), a ubiquitously expressed nuclear protein, acts by interacting with DNA and protein and is involved in widely varying cellular functions. Despite its importance, the mechanism(s) that regulate naturally occurring LEDGF activity are unidentified. Here we...

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Bibliografiske detaljer
Main Authors: Ishihara, Keiichi, Fatma, Nigar, Bhargavan, Biju, Chhunchha, Bhavana, Kubo, Eri, Dey, Sanjib, Takamura, Yoshihiro, Kumar, Anil, Singh, Dhirendra P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470485/
https://ncbi.nlm.nih.gov/pubmed/22748127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08686.x
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