LEDGF DeSumoylation by Sumo-Specific Protease, Senp-1 Regulates Its Transcriptional Activation of Small Heat Shock Protein and Cellular Response

Lens epithelium-derived growth factor (LEDGF), a ubiquitously expressed nuclear protein, acts by interacting with DNA and protein and is involved in widely varying cellular functions. Despite its importance, the mechanism(s) that regulate naturally occurring LEDGF activity are unidentified. Here we...

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Main Authors: Ishihara, Keiichi, Fatma, Nigar, Bhargavan, Biju, Chhunchha, Bhavana, Kubo, Eri, Dey, Sanjib, Takamura, Yoshihiro, Kumar, Anil, Singh, Dhirendra P.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470485/
https://ncbi.nlm.nih.gov/pubmed/22748127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08686.x
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