Epigenetic repression of LEDGF during UVB exposure by recruitment of SUV39H1 and HDAC1 to the Sp1-responsive elements within LEDGF promoter CpG island

Expression level of lens epithelial derived growth factor (LEDGF) is vital for LEDGF-mediated cell survival and cytoprotection against proapoptotic stimuli. We previously demonstrated that LEDGF is transcriptionally regulated by Sp1-responsive elements within a CpG island in the LEDGF promoter. Here...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhargavan, Biju, Chhunchha, Bhavana, Fatma, Nigar, Kubo, Eri, Kumar, Anil, Singh, Dhirendra P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669119/
https://ncbi.nlm.nih.gov/pubmed/23386123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23861
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