Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study

Disturbed flow (d-flow) induces atherosclerosis by regulating gene expression in endothelial cells (ECs). For further mechanistic understanding, we carried out a single-cell RNA sequencing (scRNA-seq) and scATAC-seq study using endothelial-enriched single cells from the left- and right carotid arter...

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Publicat a:Cell Rep
Autors principals: Andueza, Aitor, Kumar, Sandeep, Kim, Juyoung, Kang, Dong-Won, Mumme, Hope L., Perez, Julian I., Villa-Roel, Nicolas, Jo, Hanjoong
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801938/
https://ncbi.nlm.nih.gov/pubmed/33326796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108491
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