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NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn’s disease
Intestinal microfold cells are the primary pathway for translocation of secretory IgA (SIgA)-pathogen complexes to gut-associated lymphoid tissue. Uptake of SIgA/commensals complexes is important for priming adaptive immunity in the mucosa. This study aims to explore the effect of SIgA retrograde tr...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7801705/ https://ncbi.nlm.nih.gov/pubmed/33431850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20348-0 |
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