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Human Plasma-derived Polymeric IgA and IgM Antibodies Associate with Secretory Component to Yield Biologically Active Secretory-like Antibodies

Immunotherapy with monoclonal and polyclonal immunoglobulin is successfully applied to improve many clinical conditions, including infection, autoimmune diseases, or immunodeficiency. Most immunoglobulin products, recombinant or plasma-derived, are based on IgG antibodies, whereas to date, the use o...

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Detalhes bibliográficos
Main Authors: Longet, Stéphanie, Miled, Sarah, Lötscher, Marius, Miescher, Sylvia M., Zuercher, Adrian W., Corthésy, Blaise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567660/
https://ncbi.nlm.nih.gov/pubmed/23250751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410811
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