The Aβ(1–38) peptide is a negative regulator of the Aβ(1–42) peptide implicated in Alzheimer disease progression

The pool of β-Amyloid (Aβ) length variants detected in preclinical and clinical Alzheimer disease (AD) samples suggests a diversity of roles for Aβ peptides. We examined how a naturally occurring variant, e.g. Aβ(1–38), interacts with the AD-related variant, Aβ(1–42), and the predominant physiologic...

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Pubblicato in:Sci Rep
Autori principali: Quartey, Maa O., Nyarko, Jennifer N. K., Maley, Jason M., Barnes, Jocelyn R., Bolanos, Maria A. C., Heistad, Ryan M., Knudsen, Kaeli J., Pennington, Paul R., Buttigieg, Josef, De Carvalho, Carlos E., Leary, Scot C., Parsons, Matthew P., Mousseau, Darrell D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801637/
https://ncbi.nlm.nih.gov/pubmed/33432101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80164-w
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