Platelets express adaptor proteins of the extrinsic apoptosis pathway and can activate caspase-8

BACKGROUND: Apoptotic pathways in platelets are important for their survival and function. Platelet apoptosis may be involved in the pathogenesis of immune thrombocytopenia (ITP), an autoimmune-mediated disease. In contrast to the intrinsic apoptosis pathway, not much is known about the extrinsic pa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Goelz, Nadine, Eekels, Julia J. M., Pantic, Milica, Kamber, Christoph T., Speer, Oliver, Franzoso, Francesca D., Schmugge, Markus
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7799768/
https://ncbi.nlm.nih.gov/pubmed/33428668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244848
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