Laddar...
A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis
The extrinsic apoptosis pathway is initiated by binding of death ligands to death receptors resulting in the formation of the death-inducing signaling complex (DISC). Activation of procaspase-8 within the DISC and its release from the signaling complex is required for processing executor caspases an...
Sparad:
| Huvudupphovsmän: | , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Blackwell Publishing Ltd
2014
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983683/ https://ncbi.nlm.nih.gov/pubmed/24442637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201385686 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|