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Stereospecific Cross-Coupling Reactions Provide Conformationally-Biased Arylalkanes with Anti-Leukemia Activity

A focused small library of carbamates and alcohols was prepared employing stereospecific Kumada-ring opening reactions of tetrahydropyrans. The core framework of the library members is acyclic and incorporates 1,3-substituents, to provide a conformational bias in avoiding syn-pentane interactions. A...

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Vydáno v:Isr J Chem
Hlavní autoři: Sanford, Amberly B., Tollefson, Emily J., Jarvo, Elizabeth R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7799436/
https://ncbi.nlm.nih.gov/pubmed/33442068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201900071
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