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A Unified Explanation for Chemoselectivity and Stereospecificity of Ni-Catalyzed Kumada and Cross-Electrophile Coupling Reactions of Benzylic Ethers: A Combined Computational and Experimental Study

Ni-catalyzed C(sp(3))-O bond activation provides a useful approach to synthesize enantioenriched products from readily available enantioenriched benzylic alcohol derivatives. The control of stereospecificity is key to the success of these transformations. To elucidate the reversed stereospecificity...

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Publicat a:J Am Chem Soc
Autors principals: Chen, Pan-Pan, Lucas, Erika L., Greene, Margaret A., Zhang, Shuo-Qing, Tollefson, Emily J., Erickson, Lucas W., Taylor, Buck L. H., Jarvo, Elizabeth R., Hong, Xin
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773265/
https://ncbi.nlm.nih.gov/pubmed/30866626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b00097
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