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Retention or Inversion in Stereospecific Nickel-Catalyzed Cross-Coupling of Benzylic Carbamates with Arylboronic Esters: Control of Absolute Stereochemistry with an Achiral Catalyst

Stereospecific coupling of benzylic carbamates and pivalates with aryl- and heteroarylboronic esters has been developed. The reaction proceeds with selective inversion or retention at the electrophilic carbon depending on the nature of the ligand. Tricyclohexylphosphine ligand provides product with...

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Detalhes bibliográficos
Main Authors: Harris, Michael R., Hanna, Luke E., Greene, Margaret A., Moore, Curtis E., Jarvo, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686550/
https://ncbi.nlm.nih.gov/pubmed/23414579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311783k
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