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Nickel-Catalyzed Borylation of Benzylic Ammonium Salts: Stereospecific Synthesis of Enantioenriched Benzylic Boronates

We have developed a stereospecific, nickel-catalyzed cross-coupling of secondary benzylic ammonium salts and diboronate esters to deliver highly enantioenriched benzylic boronates. This reaction utilizes amine-derived electrophiles, which are readily available in high enantiopurity, and simple, inex...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Basch, Corey H., Cobb, Kelsey M., Watson, Mary P.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809423/
https://ncbi.nlm.nih.gov/pubmed/26679212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b03455
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