Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA

Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amounts of amino acids, including arginine. L-arginine is a non-e...

Full description

Saved in:
Bibliographic Details
Published in:J Ovarian Res
Main Authors: El-Mais, Nour, Fakhoury, Isabelle, Abdellatef, Sandra, Abi-Habib, Ralph, El-Sibai, Mirvat
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7798344/
https://ncbi.nlm.nih.gov/pubmed/33423701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-021-00767-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items