Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA

Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amounts of amino acids, including arginine. L-arginine is a non-e...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Ovarian Res
Egile Nagusiak: El-Mais, Nour, Fakhoury, Isabelle, Abdellatef, Sandra, Abi-Habib, Ralph, El-Sibai, Mirvat
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7798344/
https://ncbi.nlm.nih.gov/pubmed/33423701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-021-00767-3
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