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Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA

Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amounts of amino acids, including arginine. L-arginine is a non-e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Ovarian Res
Prif Awduron: El-Mais, Nour, Fakhoury, Isabelle, Abdellatef, Sandra, Abi-Habib, Ralph, El-Sibai, Mirvat
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7798344/
https://ncbi.nlm.nih.gov/pubmed/33423701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-021-00767-3
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