NADPH oxidase-4 promotes eccentric cardiac hypertrophy in response to volume overload

AIMS: Chronic pressure or volume overload induce concentric vs. eccentric left ventricular (LV) remodelling, respectively. Previous studies suggest that distinct signalling pathways are involved in these responses. NADPH oxidase-4 (Nox4) is a reactive oxygen species-generating enzyme that can limit...

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Vydáno v:Cardiovasc Res
Hlavní autoři: Schnelle, Moritz, Sawyer, Iain, Anilkumar, Narayana, Mohamed, Belal A, Richards, Daniel A, Toischer, Karl, Zhang, Min, Catibog, Norman, Sawyer, Greta, Mongue-Din, Héloïse, Schröder, Katrin, Hasenfuss, Gerd, Shah, Ajay M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797217/
https://ncbi.nlm.nih.gov/pubmed/31821410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvz331
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