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Structure-guided engineering of TGF-βs for the development of novel inhibitors and probing mechanism

The increasing availability of detailed structural information on many biological systems provides an avenue for manipulation of these structures, either for probing mechanism or for developing novel therapeutic agents for treating disease. This has been accompanied by the advent of several powerful...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Autor principal: Hinck, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797196/
https://ncbi.nlm.nih.gov/pubmed/30026042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.07.008
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