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TGF-β antagonists: Same Knot, but Different Hold
In this issue of Structure, Nolan and colleagues present the structure of BMP antagonist, PRDC, which adopts a head-to-tail dimer with distinct structure and inhibitory mechanism compared to other dimeric antagonists of TGF-beta superfamily, such as noggin.
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809007/ https://ncbi.nlm.nih.gov/pubmed/23931139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.07.015 |
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