Persistence of mRNA indicative of Plasmodium falciparum ring-stage parasites 42 days after artemisinin and non-artemisinin combination therapy in naturally infected Malians

BACKGROUND: Malaria control in sub-Saharan Africa relies upon prompt case management with artemisinin-based combination therapy (ACT). Ring-stage parasite mRNA, measured by sbp1 quantitative reverse-transcriptase PCR (qRT-PCR), was previously reported to persist after ACT treatment and hypothesized...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Mahamar, Almahamoudou, Lanke, Kjerstin, Graumans, Wouter, Diawara, Halimatou, Sanogo, Koualy, Diarra, Kalifa, Niambele, Sidi Mohamed, Gosling, Roly, Drakeley, Chris, Chen, Ingrid, Dicko, Alassane, Bousema, Teun, Roh, Michelle E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797096/
https://ncbi.nlm.nih.gov/pubmed/33422068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03576-z
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