Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial

BACKGROUND: The World Health Organization recommendation on the use of a single low dose of primaquine (SLD-PQ) to reduce Plasmodium falciparum malaria transmission requires more safety data. METHODS: We conducted an open-label, nonrandomized, dose-adjustment trial of the safety of 3 single doses of...

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Detalles Bibliográficos
Publicado en:J Infect Dis
Main Authors: Chen, Ingrid, Diawara, Halimatou, Mahamar, Almahamoudou, Sanogo, Koualy, Keita, Sekouba, Kone, Daouda, Diarra, Kalifa, Djimde, Moussa, Keita, Mohamed, Brown, Joelle, Roh, Michelle E, Hwang, Jimee, Pett, Helmi, Murphy, Maxwell, Niemi, Mikko, Greenhouse, Bryan, Bousema, Teun, Gosling, Roly, Dicko, Alassane
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974787/
https://ncbi.nlm.nih.gov/pubmed/29342267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy014
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