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Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing

Chromatin properties are regulated by complex networks of epigenome modifications. Currently, it is unclear how these modifications interact and if they control downstream effects such as gene expression. We employed promiscuous chromatin binding of a zinc finger fused catalytic domain of DNMT3A to...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Broche, Julian, Kungulovski, Goran, Bashtrykov, Pavel, Rathert, Philipp, Jeltsch, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797067/
https://ncbi.nlm.nih.gov/pubmed/33300025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1169
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