Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained

BACKGROUND: DNA methylation and histone 3 lysine 9 (H3K9) methylation are considered as epigenetic marks that can be inherited through cell divisions. To explore the functional consequences and stability of these modifications, we employed targeted installment of DNA methylation and H3K9 methylation...

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Detaylı Bibliyografya
Yayımlandı:Epigenetics Chromatin
Asıl Yazarlar: Kungulovski, Goran, Nunna, Suneetha, Thomas, Maria, Zanger, Ulrich M, Reinhardt, Richard, Jeltsch, Albert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404288/
https://ncbi.nlm.nih.gov/pubmed/25901185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0002-z
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