Flanking sequence preference modulates de novo DNA methylation in the mouse genome

Mammalian de novo DNA methyltransferases (DNMT) are responsible for the establishment of cell-type-specific DNA methylation in healthy and diseased tissues. Through genome-wide analysis of de novo methylation activity in murine stem cells we uncover that DNMT3A prefers to methylate CpGs followed by...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Mallona, Izaskun, Ilie, Ioana Mariuca, Karemaker, Ino Dominiek, Butz, Stefan, Manzo, Massimiliano, Caflisch, Amedeo, Baubec, Tuncay
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797059/
https://ncbi.nlm.nih.gov/pubmed/33290556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1168
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker