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APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A
Many APOBEC cytidine deaminase members are known to induce ‘off-target’ cytidine deaminations in 5′TC motifs in genomic DNA that contribute to cancer evolution. In this report, we characterized APOBEC1, which is a possible cancer related APOBEC since APOBEC1 mRNA is highly expressed in certain types...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7797036/ https://ncbi.nlm.nih.gov/pubmed/33330905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1201 |
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