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Amyloid-β (Aβ42) Peptide Aggregation Rate and Mechanism on Surfaces with Widely Varied Properties: Insights from Brownian Dynamics Simulations
Amyloid-β (Aβ) plaques, which form by aggregation of harmless Aβ peptide monomers into larger fibrils, are characteristic of neurodegenerative disorders such as Alzheimer’s disease. Efforts to treat Alzheimer’s disease focus on stopping or reversing the aggregation process that leads to fibril forma...
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| Publicado no: | J Phys Chem B |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7797022/ https://ncbi.nlm.nih.gov/pubmed/32525673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c02926 |
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