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Cu(2+) Affects Amyloid-β (1–42) Aggregation by Increasing Peptide-Peptide Binding Forces
The link between metals, Alzheimer's disease (AD) and its implicated protein, amyloid-β (Aβ), is complex and highly studied. AD is believed to occur as a result of the misfolding and aggregation of Aβ. The dyshomeostasis of metal ions and their propensity to interact with Aβ has also been impli...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594192/ https://ncbi.nlm.nih.gov/pubmed/23536847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059005 |
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