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Widespread protection of RNA cleavage sites by a riboswitch aptamer that folds as a compact obstacle to scanning by RNase E

Riboswitches are thought generally to function by modulating transcription elongation or translation initiation. In rare instances, ligand binding to a riboswitch has been found to alter the rate of RNA degradation by directly stimulating or inhibiting nearby cleavage. Here we show that guanidine-in...

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Pubblicato in:Mol Cell
Autori principali: Richards, Jamie, Belasco, Joel G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796952/
https://ncbi.nlm.nih.gov/pubmed/33212019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.025
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