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Resistance to cyclin-dependent kinase (CDK) 4/6 inhibitors confers cross-resistance to other CDK inhibitors but not to chemotherapeutic agents in breast cancer cells

BACKGROUND: Combined endocrine therapy with a cyclin-dependent kinase (CDK) 4/6 inhibitor has been indicated to improve not only progression-free survival, but also overall survival in patients with hormone receptor (HR)-positive, HER2-negative advanced breast cancer. However, resistance to this com...

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Detalhes bibliográficos
Publicado no:Breast Cancer
Main Authors: Ogata, Ryohei, Kishino, Emi, Saitoh, Wataru, Koike, Yoshikazu, Kurebayashi, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796879/
https://ncbi.nlm.nih.gov/pubmed/32860163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12282-020-01150-8
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