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Anti‐cancer stem cell activity of a hedgehog inhibitor GANT61 in estrogen receptor‐positive breast cancer cells

Estradiol (E2) increases not only the cell growth but also the cancer stem cell (CSC) proportion in estrogen receptor (ER)‐positive breast cancer cells. It has been suggested that the non‐canonical hedgehog (Hh) pathway activated by E2 plays an important role in the regulation of CSC proportion in E...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Kurebayashi, Junichi, Koike, Yoshikazu, Ohta, Yusuke, Saitoh, Wataru, Yamashita, Tetsumasa, Kanomata, Naoki, Moriya, Takuya
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448645/
https://ncbi.nlm.nih.gov/pubmed/28211214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13205
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