Fludarabine, High-Dose Cytarabine and Idarubicin-Based Induction May Overcome the Negative Prognostic Impact of FLT3-ITD in NPM1 Mutated AML, Irrespectively of FLT3-ITD Allelic Burden

SIMPLE SUMMARY: The prognostic relevance of molecular aberrations in acute myeloid leukemia (AML) has been prevalently tested in patients receiving conventional 3+7 induction. Recently, there has been a renewed interest in intensified inductions, but very few data are available on the impact of the...

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Udgivet i:Cancers (Basel)
Main Authors: Minetto, Paola, Candoni, Anna, Guolo, Fabio, Clavio, Marino, Zannier, Maria Elena, Miglino, Maurizio, Dubbini, Maria Vittoria, Carminati, Enrico, Sicuranza, Anna, Ciofini, Sara, Colombo, Nicoletta, Pugliese, Girolamo, Marcolin, Riccardo, Santoni, Adele, Ballerini, Filippo, Lanino, Luca, Cea, Michele, Gobbi, Marco, Bocchia, Monica, Fanin, Renato, Lemoli, Roberto Massimo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796342/
https://ncbi.nlm.nih.gov/pubmed/33374216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010034
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