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The Role of Hypoxia-Inducible Factor Post-Translational Modifications in Regulating Its Localisation, Stability, and Activity

The hypoxia signalling pathway enables adaptation of cells to decreased oxygen availability. When oxygen becomes limiting, the central transcription factors of the pathway, hypoxia-inducible factors (HIFs), are stabilised and activated to induce the expression of hypoxia-regulated genes, thereby mai...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Albanese, Adam, Daly, Leonard A., Mennerich, Daniela, Kietzmann, Thomas, Sée, Violaine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796330/
https://ncbi.nlm.nih.gov/pubmed/33383924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010268
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