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Crucial Role of FABP3 in αSyn-Induced Reduction of Septal GABAergic Neurons and Cognitive Decline in Mice

In synucleinopathies, while motor symptoms are thought to be attributed to the accumulation of misfolded α-synuclein (αSyn) in nigral dopaminergic neurons, it remains to be elucidated how cognitive decline arises. Here, we investigated the effects of distinct αSyn strains on cognition and the relate...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Matsuo, Kazuya, Yabuki, Yasushi, Melki, Ronald, Bousset, Luc, Owada, Yuji, Fukunaga, Kohji
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795765/
https://ncbi.nlm.nih.gov/pubmed/33401521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010400
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