Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain

Oligomerization and/or aggregation of α-synuclein (α-Syn) triggers α-synucleinopathies such as Parkinson’s disease and dementia with Lewy bodies. It is known that α-Syn can spread in the brain like prions; however, the mechanism remains unclear. We demonstrated that fatty acid binding protein 3 (FAB...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Yabuki, Yasushi, Matsuo, Kazuya, Kawahata, Ichiro, Fukui, Naoya, Mizobata, Tomohiro, Kawata, Yasushi, Owada, Yuji, Shioda, Norifumi, Fukunaga, Kohji
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139546/
https://ncbi.nlm.nih.gov/pubmed/32210174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21062230
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