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On the Use of the Discrete Constant pH Molecular Dynamics to Describe the Conformational Space of Peptides

Solvent pH is an important property that defines the protonation state of the amino acids and, therefore, modulates the interactions and the conformational space of the biochemical systems. Generally, this thermodynamic variable is poorly considered in Molecular Dynamics (MD) simulations. Fortunatel...

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Bibliographic Details
Published in:Polymers (Basel)
Main Authors: Privat, Cristian, Madurga, Sergio, Mas, Francesc, Rubio-Martínez, Jaime
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795291/
https://ncbi.nlm.nih.gov/pubmed/33383731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym13010099
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