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On the Use of the Discrete Constant pH Molecular Dynamics to Describe the Conformational Space of Peptides

Solvent pH is an important property that defines the protonation state of the amino acids and, therefore, modulates the interactions and the conformational space of the biochemical systems. Generally, this thermodynamic variable is poorly considered in Molecular Dynamics (MD) simulations. Fortunatel...

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Detalhes bibliográficos
Publicado no:Polymers (Basel)
Main Authors: Privat, Cristian, Madurga, Sergio, Mas, Francesc, Rubio-Martínez, Jaime
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795291/
https://ncbi.nlm.nih.gov/pubmed/33383731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym13010099
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