Serotonin/5-HT1A Signaling in the Neurovascular Unit Regulates Endothelial CLDN5 Expression

We previously reported that site-selective claudin-5 (CLDN5) breakdown and protein kinase A (PKA) activation are observed in brain microvessels of schizophrenia, but the underlying molecular basis remains unknown. The 5-HT1 receptors decline the intracellular cAMP levels and inactivate the major dow...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Sugimoto, Kotaro, Ichikawa-Tomikawa, Naoki, Nishiura, Keisuke, Kunii, Yasuto, Sano, Yasuteru, Shimizu, Fumitaka, Kakita, Akiyoshi, Kanda, Takashi, Imura, Tetsuya, Chiba, Hideki
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795278/
https://ncbi.nlm.nih.gov/pubmed/33383868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010254
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars