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Conservation of 5-HT(1A) receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis

Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT(1A) autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as anxiety disorders and depression, as well as in th...

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Bibliografiske detaljer
Main Authors: Araragi, Naozumi, Mlinar, Boris, Baccini, Gilda, Gutknecht, Lise, Lesch, Klaus-Peter, Corradetti, Renato
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731744/
https://ncbi.nlm.nih.gov/pubmed/23935583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00097
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