Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann–Pick Disease Type C Model Mice

Niemann–Pick disease type C (NPC) is a recessive hereditary disease caused by mutation of the NPC1 or NPC2 gene. It is characterized by abnormality of cellular cholesterol trafficking with severe neuronal and hepatic injury. In this study, we investigated the potential of glycoprotein nonmetastatic...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Int J Mol Sci
Κύριοι συγγραφείς: Fukaura, Madoka, Ishitsuka, Yoichi, Shirakawa, Seiichi, Ushihama, Naoki, Yamada, Yusei, Kondo, Yuki, Takeo, Toru, Nakagata, Naomi, Motoyama, Keiichi, Higashi, Taishi, Arima, Hidetoshi, Kurauchi, Yuki, Seki, Takahiro, Katsuki, Hiroshi, Higaki, Katsumi, Matsuo, Muneaki, Irie, Tetsumi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2021
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795151/
https://ncbi.nlm.nih.gov/pubmed/33466390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010452
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