Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway

Cardiac hypertrophy is a major risk factor for heart failure and leads to cardiovascular morbidity and mortality. Doxorubicin (DOX) is regarded as one of the most potent anthracycline antibiotic agents; however, its clinical usage has some limitations because it has serious cardiotoxic side effects...

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Veröffentlicht in:Molecules
Hauptverfasser: Yoon, Jung Joo, Son, Chan Ok, Kim, Hye Yoom, Han, Byung Hyuk, Lee, Yun Jung, Lee, Ho Sub, Kang, Dae Gill
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795060/
https://ncbi.nlm.nih.gov/pubmed/33374365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26010053
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