HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)

The Intact Proviral DNA Assay (IPDA) was developed to address the critical need for a scalable method for intact HIV-1 reservoir quantification. This droplet digital PCR-based assay simultaneously targets two HIV-1 regions to distinguish genomically intact proviruses against a large background of de...

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Publicado no:Nat Commun
Main Authors: Kinloch, Natalie N., Ren, Yanqin, Conce Alberto, Winiffer D., Dong, Winnie, Khadka, Pragya, Huang, Szu Han, Mota, Talia M., Wilson, Andrew, Shahid, Aniqa, Kirkby, Don, Harris, Marianne, Kovacs, Colin, Benko, Erika, Ostrowski, Mario A., Del Rio Estrada, Perla M., Wimpelberg, Avery, Cannon, Christopher, Hardy, W. David, MacLaren, Lynsay, Goldstein, Harris, Brumme, Chanson J., Lee, Guinevere Q., Lynch, Rebecca M., Brumme, Zabrina L., Jones, R. Brad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794580/
https://ncbi.nlm.nih.gov/pubmed/33420062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20442-3
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