Valproic acid-exposed astrocytes impair inhibitory synapse formation and function

Valproic acid (VPA) is widely prescribed to treat epilepsy. Maternal VPA use is, however, clinically restricted because of the severe risk that VPA may cause neurodevelopmental disorders in offspring, such as autism spectrum disorder. Understanding the negative action of VPA may help to prevent VPA-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Takeda, Kotomi, Watanabe, Takuya, Oyabu, Kohei, Tsukamoto, Shuntaro, Oba, Yuki, Nakano, Takafumi, Kubota, Kaori, Katsurabayashi, Shutaro, Iwasaki, Katsunori
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794250/
https://ncbi.nlm.nih.gov/pubmed/33420078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79520-7
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