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PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential

PD-1/PD-L1 immune checkpoint inhibitors show potential for cervical cancer treatment. However, low response rates suggest that patient selection based on PD-L1 protein expression is not optimal. Here, we evaluated different PD-L1 detection methods and studied transcriptional regulation of PD-L1/PD-L...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rotman, Jossie, den Otter, Leontine A. S., Bleeker, Maaike C. G., Samuels, Sanne S., Heeren, A. Marijne, Roemer, Margaretha G. M., Kenter, Gemma G., Zijlmans, Henry J. M. A. A., van Trommel, Nienke E., de Gruijl, Tanja D., Jordanova, Ekaterina S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793653/
https://ncbi.nlm.nih.gov/pubmed/33424844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.596825
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