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CD14(+) macrophage-like cells as the linchpin of cervical cancer perpetrated immune suppression and early metastatic spread: A new therapeutic lead?

A number of studies point to an aberrant differentiation and accumulation of CD14(+) PD-L1(+) M2-macrophage-like cells in the microenvironment of cervical cancer, which promote immunosuppressive conditions and are associated with tumor invasion, angiogenesis and metastasis. Therapeutic targeting of...

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Pubblicato in:Oncoimmunology
Autori principali: Heeren, A Marijne, Kenter, Gemma G, Jordanova, Ekaterina S, de Gruijl, Tanja D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485785/
https://ncbi.nlm.nih.gov/pubmed/26155430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1009296
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