Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases

BACKGROUND: Tumors avoid destruction by cytotoxic T cells (CTL) and natural killer (NK) cells by downregulation of classical human leukocyte antigens (HLA) and overexpression of non-classical HLA. This is the first study to investigate HLA expression in relation to histology (squamous cell carcinoma...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Ferns, Debbie M., Heeren, A. Marijne, Samuels, Sanne, Bleeker, Maaike C. G., de Gruijl, Tanja D., Kenter, Gemma G., Jordanova, Ekaterina S.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109766/
https://ncbi.nlm.nih.gov/pubmed/27895918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-016-0184-3
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