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Super-resolution visualization of distinct stalled and broken replication fork structures

Endogenous genotoxic stress occurs in healthy cells due to competition between DNA replication machinery, and transcription and topographic relaxation processes. This causes replication fork stalling and regression, which can further collapse to form single-ended double strand breaks (seDSBs). Super...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Whelan, Donna R., Lee, Wei Ting C., Marks, Frances, Kong, Yu Tina, Yin, Yandong, Rothenberg, Eli
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793303/
https://ncbi.nlm.nih.gov/pubmed/33370257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009256
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