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Super-resolution visualization of distinct stalled and broken replication fork structures

Endogenous genotoxic stress occurs in healthy cells due to competition between DNA replication machinery, and transcription and topographic relaxation processes. This causes replication fork stalling and regression, which can further collapse to form single-ended double strand breaks (seDSBs). Super...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Whelan, Donna R., Lee, Wei Ting C., Marks, Frances, Kong, Yu Tina, Yin, Yandong, Rothenberg, Eli
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793303/
https://ncbi.nlm.nih.gov/pubmed/33370257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009256
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