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Increased prostaglandin-D(2) in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation
Cardiac levels of the signal transducer and activator of transcription factor-3 (STAT3) decline with age, and male but not female mice with a cardiomyocyte-specific STAT3 deficiency conditional knockout (CKO) display premature age-related heart failure associated with reduced cardiac capillary densi...
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| Veröffentlicht in: | PLoS Biol |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793290/ https://ncbi.nlm.nih.gov/pubmed/33370269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000739 |
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